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IMPACTT Newsletter | April 2023
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Welcome to our April 2023 IMPACTT newsletter. Keep reading for news, events, and publications in the microbiome world.
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Having IMPACTT Symposium Early-Bird Deadline: 10 May 2023
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Our symposium is happening July 10-12, 2023 in Canmore, AB. Our full program is now available on our website, and we recently posted an informational video about our symposium to YouTube.
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CBW-IMPACTT Microbiome Analysis Workshop Early-Bird Deadline: 05 May 2023
IMPACTT and Bioinformatics.ca have teamed up to organize the CBW-IMPACTT Microbiome Analysis Workshop, happening July 5-7, 2023 at the University of Calgary!
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This is a great opportunity to learn how to analyze data gathered from microbiome experiments. The deadline to receive our early-bird rates is this Friday, May 5, 2023. Apply today!
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IMPACTT TEAM & NETWORK NEWS
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Dr. Anita Kozyrskyj (Platform 2 Lead) and Dr. Laura Sycuro (Platform 4 Lead), along with Dr. Maria Ospina (nominated PI, Queen's University) received a CIHR Project Grant to study how social factors, together with the maternal gut microbiota, shapes mental health and neurodevelopment. This unique cohort will be based out of Edmonton and will capitalize on well-established community partnerships to recruit geographically and socioeconomically diverse populations, as well as Black, Immigrant, and Metis women. Congratulations!
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Dr. Laura Sycuro (Platform 4 Lead) received an NSERC Discovery Grant to examine the adhesion/invasion behaviors of human microbiota with a systems biology approach. Congratulations!
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Dr. Daniel Castañeda Mogollón joins Dr. Laura Sycuro’s lab as a Postdoctoral Fellow on May 15th. Dr. Castañeda Mogollón received an Eyes High Fellowship to study mechanisms through which the gut microbiome contributes to Type I Diabetes and will be working on the CMI2-funded project co-led by Dr. Laura Sycuro (Platform 4 Lead), Dr. Kathy McCoy (IMPACTT Director & Platform 1 Lead), Dr. Pere Santamaria (University of Calgary), and Dr. Jayne Danska (IMPACTT Sex & Gender Lead). Welcome, Dr. Castañeda Mogollón!
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New IMPACTT Publication
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Arab et al. (with Platform 5 Co-Lead Dr. Fiona Brinkman as senior author). Bioinformatics Advances. 06 Jan 2023.
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Highlights: GlobeCorr.ca is a web-based application designed to provide user-friendly, interactive visualization and analysis of complex omics datasets. “[It] creates a dynamic visualization using ribbons to represent positive and negative correlations, optionally grouped by domain/category (such as microbiome taxa against other metadata). GlobeCorr… provides a simple method for users to visualize and summarize complex datasets.” Visit globecorr.ca to get started!
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New Publications in the Microbiome World
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Nearing et al. (with CMI2 Team Grant Lead Dr. Morgan Langille as senior author). npj Biofilms and Microbiomes. 01 May 2023.
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Highlights: In this study, the researchers investigated the potential for the human microbiome to be used as a biomarker for prostate, breast, and colon cancer. They collected saliva samples from 89 retrospective and 260 prospective cancer cases, matched to non-cancer controls, and sequenced them using 16S rRNA gene sequencing. No significant differences in alpha diversity were found among sample types, and most beta diversity measures were non-significant, except one distance metric in retrospective breast cancer cases, and three distance metrics in colon cancer. Differential abundance analysis identified several taxa that were associated with a previous cancer diagnosis for all three cancer types, depending on the tool used. Based on their results, the authors conclude that it is unlikely that reliable oral biomarkers for breast and prostate cancer exist, but do recommend further research into the oral microbiome and colon cancer.
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Fan et al. BMC Medicine. 28 Apr 2023.
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Highlights: There is evidence that tobacco use (including smoking) can contribute to perturbations in the gut microbiota composition. In this study, the researchers used a two-sample bidirectional Mendelian randomization (MR) approach to integrate summary data of previously-published genome-wide association studies (GWASs) to identify causal associations between tobacco smoking and gut microbiota composition. They confirmed results from previous studies that smoking affected three taxa (Intestinimonas, Catenibacterium, and Ruminococcaceae) and found new evidence to suggest that an additional 13 taxa may be affected by tobacco smoking. They also found evidence that suggests that smoking behaviours could be a potential consequence of specific taxa abundance, including Actinobacteria, likely involving neurotransmitter-associated metabolites.
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New Publications from our IMPACTT Team and Network
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Dr. William Hsiao & Dr. Fiona Brinkman (Platform 5 Co-Leads)
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Rabbani et al. Population Medicine. 26 Apr 2023.
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Dr. Thomas Murooka, Dr. Adam Burgener, & Dr. Vanessa Poliquin (CMI2 Team Grant Leads)
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Fujishima et al. Mucosal Immunology. 29 Apr 2023.
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Dr. Stuart Turvey & Dr. Meghan Azad (CMI2 Team Grant Leads)
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Lishman et al. BMJ Open. 04 Apr 2023.
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Dr. Jens Walter & Dr. Benjamin Willing (IMPACTT Co-Applicants)
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Montenegro et al. Advances in Nutrition. 07 Apr 2023.
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Dr. Adam Burgener & Dr. Vanessa Poliquin (CMI2 Team Grant Leads)
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Govia et al. Clinical and Experimental Obstetrics & Gynecology. 19 Apr 2023.
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Dr. Marie-Claire Arrieta (Platform 2 Co-Lead)
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Mercer & Arrieta. Gut Microbes. 30 Apr 2023.
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Heirali et al. Open Forum Infectious Diseases. 12 Apr 2023.
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Dr. Joe Harrison (Platform 3 Co-Lead)
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Razvi et al. Microbiology Spectrum. 29 Apr 2023.
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Dr. Celia Greenwood (Platform 5 Lead)
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Su et al. Scientific Reports. 17 Apr 2023.
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Dr. Benjamin Willing (IMPACTT Co-Applicant)
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Marcolla et al. Applied and Environmental Microbiology. 26 Apr 2023.
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Dr. Eytan Wine (IMPACTT Co-Applicant)
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Foster et al. The Journal of Pediatrics. 03 Apr 2023.
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Dr. Robert Beiko (IMPACTT Co-Applicant)
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Hendricks. Scientific Reports. 30 Mar 2023.
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Dr. John Conly (IMPACTT Co-Applicant)
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Mitchell et al. JAMA Network Open. 20 Apr 2023.
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Rosca et al. Tropical Medicine and Infectious Disease
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Dr. Janet Hill (IMPACTT Co-Applicant)
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Shvartsman et al. Infection and Immunity. 22 Apr 2023.
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Dr. Thomas Louie (IMPACTT Co-Applicant)
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Gonzales-Luna et al. The Lancet Infectious Diseases. 13 Apr 2023.
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Louie et al. JAMA. 15 Apr 2023.
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Dr. Jens Walter (IMPACTT Co-Applicant)
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Archer et al. Microbiome Research Reports. 15 Apr 2023.
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Dr. Wendy Lou (CMI2 Team Grant Lead)
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Dama et al. Psychiatry Research. 25 Apr 2023.
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Dr. David Mack (CMI2 Team Grant Lead)
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Gladkikh et al. Journal of the Canadian Association of Gastroenterology. 29 Mar 2023.
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Dr. Roger Paredes (CMI2 Team Grant Lead)
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Quero et al. One Health. 13 Apr 2023.
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Brown et al. Infectious Diseases and Therapy. 19 Apr 2023.
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Dr. Jonathan Schertzer (CMI2 Team Grant Lead)
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Fang et al. Gut. 27 Apr 2023.
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Dr. Shazeen Suleman (CMI2 Team Grant Lead)
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Leps et al. Paediatrics & Child Health. 24 Apr 2023.
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Dr. Michael Surette (CMI2 Team Grant Lead)
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Zakia et al. PLOS One. 13 Apr 2023.
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Tsang et al. Microbiology Spectrum. 27 Apr 2023.
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Dr. Carolina Tropini (CMI2 Team Grant Lead)
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Cotton et al. Trends in Microbiology. 24 Apr 2023.
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Dr. Stuart Turvey (CMI2 Team Grant Lead)
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Tan et al. Journal of Clinical Immunology. 28 Apr 2023.
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Dr. Bruce Vallance (CMI2 Team Grant Lead)
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Nitschke et al. Paediatric and Perinatal Epidemiology. 28 Mar 2023.
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Dr. Emma Allen-Vercoe (CMI2 Team Grant Lead)
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Frame et al. Carbohydrate Research. 04 Apr 2023.
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Gianetto-Hill et al. Current Protocols. 24 Apr 2023.
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Dr. Gerald Giesbrecht (CMI2 Team Grant Lead)
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Bajaj et al. International Journal of Eating Disorders. 30 Mar 2023.
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Dr. Anne Marie Griffiths (CMI2 Team Grant Lead)
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Bashir et al. Quality of Life Research. 01 Apr 2023.
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Dr. Steven Kembel (CMI2 Team Grant Lead)
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Parizadeh et al. Microbiology. 21 Apr 2023.
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Dr. Tony Lam (CMI2 Team Grant Lead)
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Zhang et al. Cell Metabolism. 14 Apr 2023.
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Dr. Zulfiqar Bhutta (CMI2 Team Grant Lead)
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Imdad et al. Cochrane Database of Systematic Reviews. 30 Mar 2023.
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Padhani et al. Nutrition Reviews. 04 Apr 2023.
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Owais et al. PLOS Global Public Health. 12 Apr 2023.
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Ahmad et al. Journal of the Hellenic Veterinary Medical Society. 18 Apr 2023.
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Von Dadelszen et al. BJOG: An International Journal of Obstetrics and Gynaecology. 24 Apr 2023.
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UPCOMING EVENTS AND REMINDERS
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Click here to see curated lists of upcoming events in the microbiome world
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IMPACTT Microbiome Standards
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Our four Microbiome Standards are ready to ship across Canada and internationally, and they’re FREE for Canadian labs. (Not in Canada? Just pay shipping.) Click here to learn more and sign up to receive your standards.
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Be a contributor to our microbiome community!
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