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IMPACTT Newsletter | April 2022
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Welcome to our April 2022 newsletter. We have a lot of exciting announcements and upcoming events you won't want to miss out on, so let's dive in!
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IMPACTT TEAM & NETWORK NEWS
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Having IMPACTT 2: Advancing Microbiome Research Symposium
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IMPACTT Workshops
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Space is now full for both our Gnotobiotic Workshop (May 30-31, 2022) and our Bioinformatics Workshop (May 30 - June 1, 2022), both taking place at the University of Calgary. Thank you to everyone who registered! Keep your eye on this space for upcoming workshop announcements!
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Mini Medical School
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Dr. Markus Geuking (Education Lead) gave a lecture on Cancer Treatment and the Microbiome on April 11, 2022 as part of the University of Calgary's Mini Medical School for the General Public series, hosted by the Snyder Institute for Chronic Diseases. Click here to listen to this and older episodes.
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CONGRATULATIONS ARE IN ORDER
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Dr. Zulfiqar Bhutta Receives Canada Gairdner Award
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Dr. Zulfiqar Bhutta (CMI2 Team Grant Lead) received a 2022 Canada Gairdner Award. The Gairdner Awards recognize the world's most creative and accomplished biomedical scientists who are advancing humanity and the world. Congratulations, Dr. Bhutta!
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Kirsten Wilson and Sharon Dong Defend MSc
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Two of Dr. Markus Geuking's (Education Lead) graduate students have successfully defended their Master's Theses. Congratulations to Kirsten Wilson and Sharon Dong!
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Welcome to Dr. Shokouh Ahmadi
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Dr. Shokouh Ahmadi who will be joining the lab of Dr. Markus Geuking (Education Lead) as an Eyes High Postdoctoral Fellow at the University of Calgary this month. Welcome, Dr. Ahmadi!
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New IMPACTT Publication
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Jiang et al. (including IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, Sex & Gender Lead Dr. Jayne Danska, Platform 2 Lead and Co-Lead Dr. Anita Kozyrskyj and Dr. Marie-Claire Arrieta, IMPACTT Co-Applicant Irina Dinu, and Platform 5 Lead Dr. Celia Greenwood as senior authors). Computational and Structural Biotechnology Journal. 27 April 2022.
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Highlights: In this method article, the authors demonstrate the challenges researchers face when performing sample size and power calculations for microbiome study design. They describe and illustrate three strategies for obtaining realistic distance matrices. Using data from the American Gut project, the authors provide tables of observed distances, as well as R codes for generating similar matrices in other datasets. This code and illustrative distance tables are provided by the IMPACTT Consortium as a resource to the microbiome research community.
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New Publications in the Microbiome World
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Nanjundappa et al. (including Education Lead Dr. Markus Geuking as senior author). Cellular and Molecular Life Sciences. 04 Apr 2022.
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Highlights: The intestinal microbiota influences the development and function of both local and peripheral organs, as well as the systemic immune system. However, less is known about how the intestinal microbiota impacts T cell ontogeny in the thymus. In this review, the authors discuss recent findings in the emerging field of the gut-thymus axis, and highlight the current questions and challenges in the field.
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Gutierrez et al. (including Platform 2 Co-Lead Dr. Marie-Claire Arrieta and Education Co-Lead Dr. Braedon McDonald as senior authors). Mucosal Immunology. 26 Apr 2022.
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Highlights: The mycobiome (fungal microbiome) is an important modulator of mucosal and systemic immunity. In this review, the authors discuss current knowledge on the factors that govern host-fungi interactions in the gastrointestinal tract, and immunological outcomes in both mucosal and systemic compartments.
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Reyna et al. (including Platform 2 Lead Dr. Anita L. Kozyrskyj, and CMI2 Team Grant Leads Dr. Wendy Lou, Dr. Stuart E. Turvey, Dr. Padmaja Subbarao, & Dr. Meghan Azad) International Journal of Obesity. 15 Apr 2022.
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Highlights: In this study, researchers used group-based trajectory modeling to identify BMI trajectories from birth to 5 years of age in 3059 children. They found that infants with a rapid growth trajectory were less likely to have been breastfed, and gained less microbiota diversity in their first year of life. The results highlight the causative link between growth rate/weight gain and the microbiota, and support a novel avenue of research targeted on tangible interventions to reduce childhood obesity.
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Mirza et al. (including Platform 5 Co-Lead Dr. William Hsiao). Multiple Sclerosis and Related Disorders. 23 Apr 2022.
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Highlights: In this study, researchers examined the metabolic potential of the gut microbiome in pediatric-onset multiple sclerosis (MS) patients. MS patients had different microbiome-related metabolic potentials compared with healthy controls, including higher breakdown of lipopolysaccharide molecules, but lower resistant starch metabolism.
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New Publications from our IMPACTT Team and Network
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Dr. Fiona Brinkman (Platform 5 Co-Lead)
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Rey et al. Transplantation. 29 April 2022.
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Dr. Ian Lewis (Platform 4 Co-Lead)
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Wong Fok Lung et al. Cell Metabolism. 11 April 2022.
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Bihan et al. PLOS ONE. 20 April 2022.
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Rydzak et al. Nature Communications. 28 April 2022.
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Dr. Celia Greenwood (Platform 5 Lead)
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Lu et al. Genetics in Medicine. 23 April 2022.
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Dr. Michael Surette and Dr. Jonathan Schertzer (CMI2 Team Grant Leads)
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Broadfield et al. Molecular Metabolism. 21 April 2022.
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Dr. Anne Griffiths (CMI2 Team Grant Lead)
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Rinawi et al. Journal of Pediatric Surgery. 04 Apr 2022.
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Dr. Robert Bandsma (CMI2 Team Grant Lead)
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Gonzales et al. eBioMedicine. 07 Apr 2022.
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The Childhood Acute Illness and Nutrition (CHAIN) Network. The Lancet Global Health. 12 April 2022.
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Dr. Steven Kembel (CMI2 Team Grant Lead)
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De Bellis et al. Ecology. 12 April 2022.
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Dr. Wendy Lou (CMI2 Team Grant Lead)
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Diep et al. Psychiatry Research. 16 April 2022.
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Dr. Roger Paredes (CMI2 Team Grant Lead)
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Moltó al. Journal of Antimicrobial Chemotherapy. 15 April 2022.
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Dr. Jeremy Hirota (CMI2 Team Grant Lead)
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Hanson et al. Laboratory Investigation. 18 April 2022.
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Dr. Stuart E. Turvey (CMI2 Team Grant Lead)
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Maestre-Batlle et al. Indoor Air. 19 April 2022.
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Dr. Benjamin Willing (CMI2 Team Grant Lead)
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Pauline et al. Journal of Parenteral and Enteral Nutrition. 05 April 2022.
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Dr. Aleixo Muise & Dr. Jessie Hulst (CMI2 Team Grant Leads)
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Marwaha et al. Gastroenterology. 28 April 2022.
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Dr. Jens Walter (CMI2 Team Grant Lead)
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Walsh et al. Comprehensive Reviews in Food Science and Food Safety. April 2022.
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Dr. Zulfiqar A. Bhutta (CMI2 Team Grant Lead)
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Giuliani et al. American Journal of Obstetrics and Gynecology. 19 April 2022.
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Osendarp et al. Nature. 21 April 2022.
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Baxter et al. Cochrane Database of Systematic Reviews. 21 April 2022.
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Vaivada et al. The Lancet. 27 April 2022.
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Victora et al. The Lancet. 30 April 2022.
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Kruk et al. The Lancet. 27 April 2022.
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Black et al. The Lancet. 30 April 2022.
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UPCOMING EVENTS AND REMINDERS
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Click here to see curated lists of upcoming events in the microbiome world.
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CALL FOR PAPERS
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Neuropharmacology has an upcoming special issue on Microbiome & the Brain: Mechanisms & Maladies with guest editors Dr. María R. Aburto and Dr. John F. Cryan. Deadline: 1 September 2022.
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Be a contributor to our microbiome community!
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