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IMPACTT Newsletter | June 2021
Dear reader,
This past June has been quite eventful with the celebration of our first Microbiome Symposium, and World Microbiome Day 2021. In this newsletter, we gathered some of the resources highlighting our activities as well as new publications from our network of microbiome experts.
Happy reading!

NEWSROOM
Having-IMPACTT-success-cover
Thanks to our speakers, attendees and sponsors, our Microbiome Symposium was a success! People from around the world joined us to get infused with thriving microbiome research. Read more.
What-is-IMPACTT-cover
7 min to learn about our aims, expertise, network and activities with our Director Dr. Kathy McCoy. Video officially released on our website.
Exploring-the-Microbiome-cover-mediaplanet
From Health to Diseases to unravelling the Microbiome of extreme environments, this special campaign by Media Planet highlights cutting-edge and promising microbiome research and technical expertise across Canada. Features many microbiome experts from our microbiome network!

Spotlight on some of the articles
The Microbiome Holds a Key to Human and Environmental Health. Features the International Microbiome Centre and expertise of the core.
What is the Canadian Microbiome Initiative, what has it accomplished and what potential does it hold for the future? Explains the quintessence of our core and CMI2
Manipulating the Microbiome to Prevent Type 1 Diabetes. Highlights Dr. Danska's work, IMPACTT Sex and Gender champion.
Are Your Drugs Right for Your Gut? Highlights Dr. Figeys' work.
Nutrition and the Gut Microbiome. Highlights Dr. Marette's work.
Discover more thrilling microbiome research, HERE!
Let-them-eat-diret-documetary
Check out the documentary from the best-seller book "Let them eat dirt" by Dr. Arrieta & Dr. Finlay - A series of 5 short documentaries to understand how microbes living in our bodies influence childhood development. What steps parents can take to positively impact their child’s long-term health?

ON THE RESEARCH SIDE

From the Canadian network

#Earlylife #EnvironmentalFactors #Diet #Prebiotics #Probiotics
Composition and Associations of the Infant Gut Fungal Microbiota with Environmental Factors and Childhood Allergic Outcomes. Boutin RCT, et al. mBio. 2021 Jun - The authors characterized the gut mycobiota in 343 infants from the CHILD Cohort Study, defined associations among gut mycobiota community composition and environmental factors for the development of inhalant allergic sensitization. Using these data, they built a predictive model for inhalant atopy status at age 5 years.
Dietary fat and low fiber in purified diets differently impact the gut-liver axis to promote obesity-linked metabolic impairments. Daniel N, et al. Am J Physiol Gastrointest Liver Physiol. 2021 Jun - In this study, the authors used a mouse model to determine the key dietary factors affecting gut microbiome and how they contribute to obesity and other metabolic diseases like type 2 diabetes. See the press release.
Changes in the gut microbiome associated with infliximab in patients with bipolar disorder. Bharwani A, et al. Brain Behav. 2021 Jun - In this randomized clinical study, the authors explore the effects of a novel treatment for bipolar disorder (BD), infliximab, on the gut microbiome.
Prebiotic enriched exclusive enteral nutrition suppresses colitis via gut microbiome modulation and expansion of anti-inflammatory T cells in a mouse model of colitis. Healey GR, et al. Cell Mol Gastroenterol Hepatol. 2021 Jun - In this study, the authors examined the effects of exclusive enteral nutrition inulin-type fructans on colitis development, the gut microbiome and CD4+ T cells using an adoptive T cell transfer model of colitis.
Probiotics, prebiotics, synbiotics, and fecal microbiota transplantation in the treatment of behavioral symptoms of autism spectrum disorder: A systematic review. Tan Q, et al. Autism Res. 2021 Jun - This systematic review aims to provide an overview and critically evaluate the current evidence on the efficacy and safety of probiotic, prebiotic, synbiotic, and fecal microbiota transplantation therapies for core and co-occurring behavioral symptoms in individuals with ASD.
n individuals with ASD.

New methodologies #Metagenomics #Storage #Model
Handling of spurious sequences affects the outcome of high-throughput 16S rRNA gene amplicon profiling. Reitmeier S, et al. ISME Communication. 2021 Jun - The authors highlight the existence of fictitious sequences in 16S rRNA dataset and propose solutions for meaningful results.
The maintenance of microbial community in human fecal samples by a cost effective preservation buffer. Wu C, et al. Sci Rep. 2021 Jun - Performing shotgun metagenomic sequencing, the authors demonstrated that microbial consortia in human fecal samples were preserved in self-made preservation buffer.
Design of synthetic human gut microbiome assembly and butyrate production. Clark RL, et al. Nat Commun. 2021 May - The authors developed a model-guided approach to design synthetic human gut microbiomes to produce the health-relevant metabolite butyrate.

UPCOMING EVENTS OF INTEREST
7th-Annual-Conference
Cultivating Gut Health at the Crossroads of Food-Medicine
Targeting-Microbiota-2021
Conf-Nature-Reshaping-Microbiome-Nutrition

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