Resources By Topic
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General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome

New Paper: Moving Beyond Descriptive Studies: Harnessing Metabolomics to Elucidate the Molecular Mechanisms Underpinning Host-Microbiome Phenotypes
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj & our Platform 4 Co-Lead Dr. Ian Lewis on this recent publication! Abstract Advances in technology

New Paper: Beta-Diversity Distance Matrices for Microbiome Sample Size and Power Calculations — How to Obtain Good Estimates
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, as well as Platform 2 Leads Dr. Anita Kozyrskyj & Dr. Marie-Claire Arrieta,

New Paper: Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonization
Congratulations to our Education Leads Dr. Markus Geuking & Dr. Braedon McDonald, and IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, on this recent

New Paper: The Rise to Power of the Microbiome: Power and Sample Size Calculation for Microbiome Studies
Congratulations to our Platform 2 Leads Dr. Marie-Claire Arrieta & Dr. Anita Kozyrskyj, and Platform 5 Lead Dr. Celia Greenwood, on this recent publication! Abstract
Pregnancy & Early Life

New Paper: Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Background The gut microbiome undergoes primary ecological succession over the course

New Paper: Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Abstract Childhood obesity is linked to maternal smoking during pregnancy. Gut microbiota

New Paper: Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women
Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Objective: To determine bacterial vaginosis (BV) status at multiple time points

New Paper: Long-term and trimester-specific effects of prenatal stress on the child gut microbiota
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract ObjectiveStress is common among pregnant individuals and is associated with an
Health & Disease

New Paper: Long-Distance Relationships – Regulation of Systemic Host Defense Against Infections by the Gut Microbiota
Congratulations to our Education & Mentorship Leads Dr. Markus Geuking and Dr. Braedon McDonald on this recent publication! Abstract Despite compartmentalization within the lumen of

New Paper: Fecal Microbial Transplantation and Fiber Supplementation in Patients with Severe Obesity and Metabolic Syndrome
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Fecal microbial transplantation (FMT) from lean donors to patients with obesity

New Paper: The Hygiene Hypothesis, the COVID Pandemic, and Consequences for the Human Microbiome
Congratulations to our Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! A perspective from the Canadian Institute for Advanced Research (CIFAR) on the impact

New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth
Antimicrobial Resistance

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Ethical Health Security in the Age of Antimicrobial Resistance
Congratulations to our Ethics Lead Dr. Diego Silva on this recent publication! Abstract Owing to its potential human, social and economic costs, antimicrobial resistance (AMR)

Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children

Ethics and Anti-Microbial Resistance (AMR)
The 5th volume of the Springer Series on Public Health Ethics Analysis published by Dr. Euzebiusz Jamrozik and Dr. Michael Selgelid, focuses on Ethics and
Microbiome & Immunity

New Paper: Microbial Modulation of Intestinal T Helper Cell Responses and Implications for Disease and Therapy
Congratulations to our Education & Mentorship Lead Dr. Markus Geuking on this recent publication! This review summarizes the milestone findings in the field of microbiota-intestinal

New Paper: Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy, as well as our Education & Mentorship Lead & Co-Lead Dr. Markus Geuking and

New Paper: Microbiome-Derived Inosine Modulates Response to Checkpoint Inhibitor Immunotherapy
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy, as well as our Platform 4 Co-Lead Dr. Ian Lewis and our Education &

New Paper: Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Using a define mouse model of acute methicillin-resistant Staphylococcus aureus (MRSA) bacteremia