Resources By Topic
Keep scrolling for posts organized by topic:
General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome

New Paper: Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Whether the human fetus and the prenatal intrauterine environment (amniotic fluid

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory

New Paper: Long-Distance Relationships – Regulation of Systemic Host Defense Against Infections by the Gut Microbiota
Congratulations to our Education & Mentorship Leads Dr. Markus Geuking and Dr. Braedon McDonald on this recent publication! Abstract Despite compartmentalization within the lumen of

New Paper: From Germ-Free to Wild: Modulating Microbiome Complexity to Understand Mucosal Immunology
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The gut microbiota influences host responses at practically
Pregnancy & Early Life

New Paper: Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Background The gut microbiome undergoes primary ecological succession over the course

New Paper: Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Abstract Childhood obesity is linked to maternal smoking during pregnancy. Gut microbiota

New Paper: Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women
Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Objective: To determine bacterial vaginosis (BV) status at multiple time points

New Paper: Long-term and trimester-specific effects of prenatal stress on the child gut microbiota
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract ObjectiveStress is common among pregnant individuals and is associated with an
Health & Disease

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Ethical Health Security in the Age of Antimicrobial Resistance
Congratulations to our Ethics Lead Dr. Diego Silva on this recent publication! Abstract Owing to its potential human, social and economic costs, antimicrobial resistance (AMR)

Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children

Ethics and Anti-Microbial Resistance (AMR)
The 5th volume of the Springer Series on Public Health Ethics Analysis published by Dr. Euzebiusz Jamrozik and Dr. Michael Selgelid, focuses on Ethics and
Microbiome & Immunity

Improve Human Immunology Research with CAN-ASC
The Canadian Autoimmunity Standardization Core (CAN-ASC) was funded in 2018 by the Canadian Institutes of Health Research (CIHR) in order to provide guidance on best practices in

New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal

Tune in: bacteria may hold a key to some cancer immunotherapies
In these two podcasts, our Director and Platform 1 Lead Dr. Kathy McCoy speaks about her recent study exploring the role of inosine, a bacterial

New Paper: Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Using in vivo live imaging of infected lungs in animal models, Dr.