Resources By Topic
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General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome

New Paper: Moving Beyond Descriptive Studies: Harnessing Metabolomics to Elucidate the Molecular Mechanisms Underpinning Host-Microbiome Phenotypes
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj & our Platform 4 Co-Lead Dr. Ian Lewis on this recent publication! Abstract Advances in technology

New Paper: Beta-Diversity Distance Matrices for Microbiome Sample Size and Power Calculations — How to Obtain Good Estimates
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, as well as Platform 2 Leads Dr. Anita Kozyrskyj & Dr. Marie-Claire Arrieta,

New Paper: Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonization
Congratulations to our Education Leads Dr. Markus Geuking & Dr. Braedon McDonald, and IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, on this recent

New Paper: The Rise to Power of the Microbiome: Power and Sample Size Calculation for Microbiome Studies
Congratulations to our Platform 2 Leads Dr. Marie-Claire Arrieta & Dr. Anita Kozyrskyj, and Platform 5 Lead Dr. Celia Greenwood, on this recent publication! Abstract
Pregnancy & Early Life

Green spaces may be beneficial for early life microbiota, be outdoorsy!
Analyzing and mapping the microbiota of 355 4 month-old infants to their area of living, Dr. Kozyrskyj and her colleagues revealed that living close by

New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice
Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.
Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

New Paper: Consumption of Artificially Sweetened Beverages During Pregnancy Impacts Infant Gut Microbiota and Body Mass Index
Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.
Health & Disease

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Ethical Health Security in the Age of Antimicrobial Resistance
Congratulations to our Ethics Lead Dr. Diego Silva on this recent publication! Abstract Owing to its potential human, social and economic costs, antimicrobial resistance (AMR)

Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children

Ethics and Anti-Microbial Resistance (AMR)
The 5th volume of the Springer Series on Public Health Ethics Analysis published by Dr. Euzebiusz Jamrozik and Dr. Michael Selgelid, focuses on Ethics and
Microbiome & Immunity

New Paper: Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes and our IMPACTT Director/Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract INTRODUCTION The

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory

New Paper: Long-Distance Relationships – Regulation of Systemic Host Defense Against Infections by the Gut Microbiota
Congratulations to our Education & Mentorship Leads Dr. Markus Geuking and Dr. Braedon McDonald on this recent publication! Abstract Despite compartmentalization within the lumen of

New Paper: Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonization
Congratulations to our Education Leads Dr. Markus Geuking & Dr. Braedon McDonald, and IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, on this recent