Resources By Topic
Keep scrolling for posts organized by topic:
General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome
Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children
Video: Host-Microbe-Environment Interactions
Over the past few years, evidence has revealed the key role that microbes play in human health and disease. This short animated video highlights key
Role and Impact of the Microbiome on the Human Genome
Read about key concepts and views on the role and impact of our microbes’ genomes on our human genome! 3 recent papers to give you
New Paper: The Hygiene Hypothesis, the COVID Pandemic, and Consequences for the Human Microbiome
Congratulations to our Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! A perspective from the Canadian Institute for Advanced Research (CIFAR) on the impact
Pregnancy & Early Life
New Paper: Lessons Learned From the Prenatal Microbiome Controversy
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract For more than a century, the prenatal environment was
New Paper: Maternal Consumption of Artificially Sweetened Beverages During Pregnancy is Associated with Infant Gut Microbiota and Metabolic Modifications and Increased Infant Body Mass Index
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta and our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Studying 100 infants from
New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth
New Paper: Vitamin D Supplementation in Pregnancy and Early Infancy in Relation to Gut Microbiota Composition and C. difficile Colonization: Implications for Viral Respiratory Infections
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Studying 1,157 mother-infant pairs of the CHILD Cohort, researchers unravel a possible
Health & Disease
New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside
New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores
New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but
New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance
New Paper: Decreasing Antibiotic Use, The Gut Microbiota, and Asthma Incidence in Children: Evidence From Population-Based and Prospective Cohort Studies
The authors investigated if the decreases in asthma incidence are linked to reduced antibiotic prescribing and mediated by changes in the gut microbiota.
New Paper: CARD 2020: Antibiotic Resistome Surveillance With the Comprehensive Antibiotic Resistance Database
Describe updates and expansions to CARD, the Comprehensive Antibiotic Resistance Database, its biocuration process and resources for community biocuration.
Microbiome & Immunity
New Paper: Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes and our IMPACTT Director/Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract INTRODUCTION The
New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
New Paper: Long-Distance Relationships – Regulation of Systemic Host Defense Against Infections by the Gut Microbiota
Congratulations to our Education & Mentorship Leads Dr. Markus Geuking and Dr. Braedon McDonald on this recent publication! Abstract Despite compartmentalization within the lumen of
New Paper: Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonization
Congratulations to our Education Leads Dr. Markus Geuking & Dr. Braedon McDonald, and IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy, on this recent