Resources By Topic
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General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome

New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet

New Paper: Protease Activities of Vaginal Porphyromonas Species Disrupt Coagulation and Extracellular Matrix in the Cervicovaginal Niche
Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their

New Paper: Fecal Microbial Transplantation and Fiber Supplementation in Patients with Severe Obesity and Metabolic Syndrome
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Fecal microbial transplantation (FMT) from lean donors to patients with obesity

New Paper: Bacteroides-Dominant Gut Microbiome of Late Infancy is Associated with Enhanced Neurodevelopment
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this longitudinal clinical study, the authors leveraged the CHILD cohort study
Pregnancy & Early Life

New Paper: Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Background The gut microbiome undergoes primary ecological succession over the course

New Paper: Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Abstract Childhood obesity is linked to maternal smoking during pregnancy. Gut microbiota

New Paper: Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women
Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Objective: To determine bacterial vaginosis (BV) status at multiple time points

New Paper: Long-term and trimester-specific effects of prenatal stress on the child gut microbiota
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract ObjectiveStress is common among pregnant individuals and is associated with an
Health & Disease

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance

New Paper: Decreasing Antibiotic Use, The Gut Microbiota, and Asthma Incidence in Children: Evidence From Population-Based and Prospective Cohort Studies
The authors investigated if the decreases in asthma incidence are linked to reduced antibiotic prescribing and mediated by changes in the gut microbiota.

New Paper: CARD 2020: Antibiotic Resistome Surveillance With the Comprehensive Antibiotic Resistance Database
Describe updates and expansions to CARD, the Comprehensive Antibiotic Resistance Database, its biocuration process and resources for community biocuration.
Microbiome & Immunity

The emerging roles of eosinophils in mucosal homeostasis.
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.

New Paper: Immunological Roles of Intestinal Mesenchymal Cells
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The intestine is continuously exposed to an enormous

New Paper: Neutrophils Recirculate Through Lymph Nodes to Survey Tissues for Pathogens
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Abstract The adaptive immune function of lymph nodes is dependent on constant

New Paper: Macrophage Galactose Lectin is Critical for Kupffer Cells to Clear Aged Platelets
Congratulations to Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Abstract Early life exposure to microbes plays an important role in immune system