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General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity

General Microbiome

New Paper: Lessons Learned From the Prenatal Microbiome Controversy

Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract For more than a century, the prenatal environment was

New Paper: Maternal Consumption of Artificially Sweetened Beverages During Pregnancy is Associated with Infant Gut Microbiota and Metabolic Modifications and Increased Infant Body Mass Index

Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta and our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Studying 100 infants from

Cover Folio U of A - Dr. Kozyrskyj article Oct 2020

New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome

Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth

Fig1 Review Innate responses to gut microbiota; critical assessment of the necessary experimental controls

New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls

Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal

Green spaces may be beneficial for early life microbiota, be outdoorsy!

Analyzing and mapping the microbiota of 355 4 month-old infants to their area of living, Dr. Kozyrskyj and her colleagues revealed that living close by

New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice

Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

Fig 1. The perinatal period represents a time in development when exogenous factors that affect the microbiome such as antibiotics, diet, hygiene, pathogens, mode of birth, and pollutants can alter immune and physiological programming. The effects of early-life programming may lead to increased disease susceptibility later in life. Created with BioRender.com from The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

Fig 3. Drivers of gut bacterial beta-diversity and indicator taxa associated with maternal consumption of ASB differ between clusters. (A) Univariate models showing significance and explained variance of 10 variables on bacterial community structure across all data and each cluster subset. Horizontal bars show the amount of variance (R2) explained by each covariate in the model as determined by envfit. Asterisk denotes the significant covariates in each data subset (P

New Paper: Consumption of Artificially Sweetened Beverages During Pregnancy Impacts Infant Gut Microbiota and Body Mass Index

Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk

Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives

Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease

Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

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