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General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity

General Microbiome

New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice

Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet

New Paper: Protease Activities of Vaginal Porphyromonas Species Disrupt Coagulation and Extracellular Matrix in the Cervicovaginal Niche

Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their

New Paper: Fecal Microbial Transplantation and Fiber Supplementation in Patients with Severe Obesity and Metabolic Syndrome

Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Fecal microbial transplantation (FMT) from lean donors to patients with obesity

New Paper: Bacteroides-Dominant Gut Microbiome of Late Infancy is Associated with Enhanced Neurodevelopment

Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this longitudinal clinical study, the authors leveraged the CHILD cohort study

Green spaces may be beneficial for early life microbiota, be outdoorsy!

Analyzing and mapping the microbiota of 355 4 month-old infants to their area of living, Dr. Kozyrskyj and her colleagues revealed that living close by

New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice

Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

Fig 1. The perinatal period represents a time in development when exogenous factors that affect the microbiome such as antibiotics, diet, hygiene, pathogens, mode of birth, and pollutants can alter immune and physiological programming. The effects of early-life programming may lead to increased disease susceptibility later in life. Created with BioRender.com from The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

Fig 3. Drivers of gut bacterial beta-diversity and indicator taxa associated with maternal consumption of ASB differ between clusters. (A) Univariate models showing significance and explained variance of 10 variables on bacterial community structure across all data and each cluster subset. Horizontal bars show the amount of variance (R2) explained by each covariate in the model as determined by envfit. Asterisk denotes the significant covariates in each data subset (P

New Paper: Consumption of Artificially Sweetened Beverages During Pregnancy Impacts Infant Gut Microbiota and Body Mass Index

Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk

Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives

Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease

Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

Resources By Topic