Resources By Topic
Keep scrolling for posts organized by topic:
General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome

New Paper: Metaproteomic Profiling of Fungal Gut Colonization in Gnotobiotic Mice
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Eukaryotic microbes can modulate mammalian host health and disease states, yet

New Paper: Protease Activities of Vaginal Porphyromonas Species Disrupt Coagulation and Extracellular Matrix in the Cervicovaginal Niche
Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Porphyromonas asaccharolytica and Porphyromonas uenonis are common inhabitants of the vaginal microbiome, but their

New Paper: Fecal Microbial Transplantation and Fiber Supplementation in Patients with Severe Obesity and Metabolic Syndrome
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Fecal microbial transplantation (FMT) from lean donors to patients with obesity

New Paper: Bacteroides-Dominant Gut Microbiome of Late Infancy is Associated with Enhanced Neurodevelopment
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this longitudinal clinical study, the authors leveraged the CHILD cohort study
Pregnancy & Early Life

Green spaces may be beneficial for early life microbiota, be outdoorsy!
Analyzing and mapping the microbiota of 355 4 month-old infants to their area of living, Dr. Kozyrskyj and her colleagues revealed that living close by

New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice
Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.
Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

New Paper: Consumption of Artificially Sweetened Beverages During Pregnancy Impacts Infant Gut Microbiota and Body Mass Index
Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.
Health & Disease

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores

New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but

New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside

New Paper: Ethical Health Security in the Age of Antimicrobial Resistance
Congratulations to our Ethics Lead Dr. Diego Silva on this recent publication! Abstract Owing to its potential human, social and economic costs, antimicrobial resistance (AMR)

Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children

Ethics and Anti-Microbial Resistance (AMR)
The 5th volume of the Springer Series on Public Health Ethics Analysis published by Dr. Euzebiusz Jamrozik and Dr. Michael Selgelid, focuses on Ethics and
Microbiome & Immunity

Improve Human Immunology Research with CAN-ASC
The Canadian Autoimmunity Standardization Core (CAN-ASC) was funded in 2018 by the Canadian Institutes of Health Research (CIHR) in order to provide guidance on best practices in

New Paper: Innate Responses to Gut Microbiota; Critical Assessment of the Necessary Experimental Controls
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Focusing on the recent findings (since 2017) regarding the commensal

Tune in: bacteria may hold a key to some cancer immunotherapies
In these two podcasts, our Director and Platform 1 Lead Dr. Kathy McCoy speaks about her recent study exploring the role of inosine, a bacterial

New Paper: Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
Congratulations to our Platform 1 Co-Lead Dr. Paul Kubes on this recent publication! Using in vivo live imaging of infected lungs in animal models, Dr.