Resources By Topic
Keep scrolling for posts organized by topic:
General Microbiome
Pregnancy & Early Life
Health & Disease
Antimicrobial Resistance
Microbiome & Immunity
General Microbiome
New Paper: Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Whether the human fetus and the prenatal intrauterine environment (amniotic fluid
New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
New Paper: Long-Distance Relationships – Regulation of Systemic Host Defense Against Infections by the Gut Microbiota
Congratulations to our Education & Mentorship Leads Dr. Markus Geuking and Dr. Braedon McDonald on this recent publication! Abstract Despite compartmentalization within the lumen of
New Paper: From Germ-Free to Wild: Modulating Microbiome Complexity to Understand Mucosal Immunology
Congratulations to our IMPACTT Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! Abstract The gut microbiota influences host responses at practically
Pregnancy & Early Life
New Paper: Delayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Abstract Allergic diseases affect millions of people worldwide. An increase in their
New Paper: Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
Congratulations to our Platform 2 Co-Lead Dr. Marie-Claire Arrieta on this recent publication! Abstract Whether the human fetus and the prenatal intrauterine environment (amniotic fluid
New Paper: Bacteroides-Dominant Gut Microbiome of Late Infancy is Associated with Enhanced Neurodevelopment
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! In this longitudinal clinical study, the authors leveraged the CHILD cohort study
Documentary: Let Them Eat Dirt
Dr. Brett Finlay and Dr. Marie-Claire Arrieta (IMPACTT Platform 2 Co-Lead) have written an engaging and important book called Let Them Eat Dirt: Saving our Children
Health & Disease
New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract
Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside
New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk
Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores
New Paper: Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract Background & AimsThe cause of Crohn’s disease (CD) is unknown, but
New Paper: Immunometabolism and microbial metabolites at the gut barrier: lessons for therapeutic intervention in Inflammatory Bowel Disease
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Abstract The concept of immunometabolism has emerged recently whereby repolarizing of inflammatory
Antimicrobial Resistance
New Paper: Decreasing Antibiotic Use, The Gut Microbiota, and Asthma Incidence in Children: Evidence From Population-Based and Prospective Cohort Studies
The authors investigated if the decreases in asthma incidence are linked to reduced antibiotic prescribing and mediated by changes in the gut microbiota.
New Paper: CARD 2020: Antibiotic Resistome Surveillance With the Comprehensive Antibiotic Resistance Database
Describe updates and expansions to CARD, the Comprehensive Antibiotic Resistance Database, its biocuration process and resources for community biocuration.
Microbiome & Immunity
New Paper: Mucosal or Systemic Microbiota Exposures Shape the B Cell Repertoire
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy on this recent publication! In this intercontinental research effort between Switzerland, Norway, Germany and
New Paper: Sex-Specific Differences in the Gut Microbiome in Response to Dietary Fiber Supplementation in IL-10-Deficient Mice
Congratulations to our Platform 3 Lead Dr. Karen Madsen on this recent publication! Using (IL)-10 deficient murine colitis model, Dr. Zhang et al. investigated whether
New Paper: Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases.
Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.
New Paper: Perivascular Localization of Macrophages in the Intestinal Mucosa is Regulated by Nr4a1 and the Microbiome
A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.