New Paper: The Hygiene Hypothesis, the COVID Pandemic, and Consequences for the Human Microbiome
Congratulations to our Platform 1 Co-Lead Dr. Philippe Gros on this recent publication! A perspective from the Canadian Institute for Advanced Research (CIFAR) on the impact of the environment related to the COVID pandemic and its effects on the human microbiome. Explore many facets of COVID-19−induced societal changes and their possible effects on the microbiome, and […]
New Paper: From Birth to Overweight and Atopic Disease: Multiple and Common Pathways of the Infant Gut Microbiome
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! This recent study from Dr. Kozyrskyj’s team and colleagues highlights how birth factors from the CHILD study cohort (@CHILDSTUDY) correlate to changes in the gut microbes of infants to “determine the pathways by which these alterations may lead to an increased risk […]
Tune in: bacteria may hold a key to some cancer immunotherapies
In these two podcasts, our Director and Platform 1 Lead Dr. Kathy McCoy speaks about her recent study exploring the role of inosine, a bacterial metabolite, in response to cancer immunotherapies. Interviewer Charles Bergquist from Science Friday also raises some important questions such as the recent successes of the microbiome field (Twitter: @scifri). Richard Jacobs […]
New Paper: Microbial Modulation of Intestinal T Helper Cell Responses and Implications for Disease and Therapy
Congratulations to our Education & Mentorship Lead Dr. Markus Geuking on this recent publication! This review summarizes the milestone findings in the field of microbiota-intestinal T helper cell crosstalk with a focus on the role of specific commensal bacteria and their metabolites. They discuss mechanistic mouse studies and are linking these to human studies where […]
New Paper: Programing of an Intravascular Immune Firewall by the Gut Microbiota Protects against Pathogen Dissemination during Infection
Congratulations to our Director and Platform 1 Lead Dr. Kathy McCoy, as well as our Education & Mentorship Lead & Co-Lead Dr. Markus Geuking and Dr. Braedon McDonald, on this recent publication! Summary Eradication of pathogens from the bloodstream is critical to prevent disseminated infections and sepsis. Kupffer cells in the liver form an intravascular […]
New Paper: Vitamin D Supplementation in Pregnancy and Early Infancy in Relation to Gut Microbiota Composition and C. difficile Colonization: Implications for Viral Respiratory Infections
Congratulations to our Platform 2 Lead Dr. Anita Kozyrskyj on this recent publication! Studying 1,157 mother-infant pairs of the CHILD Cohort, researchers unravel a possible link between vitamin D supplementation during early-life and protection against C. difficile infection. Vit-D supplementation was also observed to be associated with a lower level of a specific bacterium Megamonas. […]
