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Category: General Microbiome

Posts and papers related to the microbiome at large

New Paper: Effect of chicory inulin-type fructan–containing snack bars on the human gut microbiota in low dietary fiber consumers in a randomized crossover trial

Illustration Snack Bar

This registered randomized crossover trial provides insights on whether the use of dietary supplements can fill-up the dietary fiber gap

New Paper: Decreasing Antibiotic Use, The Gut Microbiota, and Asthma Incidence in Children: Evidence From Population-Based and Prospective Cohort Studies

Fig5.b.Decreasing-antibiotic-use-the-gut-microbiota-and-asthma-incidence-in-children-evidence-from-population-based-and-prospective-cohort-studies

The authors investigated if the decreases in asthma incidence are linked to reduced antibiotic prescribing and mediated by changes in the gut microbiota.

New Paper: A Diversified Dietary Pattern Is Associated With a Balanced Gut Microbial Composition of Faecalibacterium and Escherichia/Shigella in Patients With Crohn’s Disease in Remission

Illustration about the effect of diet on the microbiota

Study the relationships between dietary intake and shifts in microbiota and their metabolites in Crohn’s Disease patients to help define a dietary pattern.

New Paper: Fecal Transplant Prevents Gut Dysbiosis and Anxiety-Like Behaviour After Spinal Cord Injury in Rats

Fig 2. Experimental Timeline. Upon arrival, rats were allowed one week to acclimate to their environment before testing. Prior to injury, baseline measures were obtained in the cylinder test, open field, light-dark box and sucrose preference tests. With the exception of the healthy group, all rats were gavaged with a fecal slurry (FMT: fecal microbiota transplant) or control solution at the time of injury and for 2 days following injury or sham surgery. Stool samples were collected for 16s rRNA sequencing prior to, 3 days and 4 weeks following surgeries. After surgeries, rats were tested weekly on a battery of behavioural tests followed by perfusions (5 weeks following surgeries) and tissue analysis.

A model of anxiety following a cervical contusion spinal cord injury in rats demonstrates fecal transplant prevents gut dysbiosis and anxiety-like behaviour

New Paper: Intestinal Fungi are Causally Implicated in Microbiome Assembly and Immune Development in Mice

Intestinal fungi are causally implicated in microbiome assembly and immune development in mice

Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Fig 1. The perinatal period represents a time in development when exogenous factors that affect the microbiome such as antibiotics, diet, hygiene, pathogens, mode of birth, and pollutants can alter immune and physiological programming. The effects of early-life programming may lead to increased disease susceptibility later in life. Created with BioRender.com from The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

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