New Paper: Longitudinal assessment of bacterial vaginosis prior to and during incident pregnancy: an observational study in Kenyan adolescent girls and young women

Congratulations to our Platform 4 Lead Dr. Laura Sycuro on this recent publication! Abstract Objective: To determine bacterial vaginosis (BV) status at multiple time points among adolescent girls and young women (AGYW) and assess the impact of pregnancy on their BV status. Design: Longitudinal cohort study. Setting: Thika, Kenya. Participants: AGYW aged 16–20 years enrolled prior to first […]

New Paper: Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

Congratulations to our Education & Mentorship Co-Lead Dr. Braedon McDonald on this recent publication! Abstract Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside of the intestine and are a major causative agent of urinary tract infections. Treatment of these infections is increasingly frustrated by antimicrobial resistance (AMR) diminishing the number of effective therapies […]

New Paper: Identifying Rare Genetic Determinants for Improved Polygenic Risk Prediction of Bone Mineral Density and Fracture Risk

Congratulations to our Platform 5 Lead Dr. Celia Greenwood on this recent publication! Abstract Osteoporosis and fractures severely impact the elderly population. Polygenic risk scores for bone mineral density have demonstrated potential clinical utility. However, the value of rare genetic determinants in risk prediction has not been assessed. With whole-exome sequencing data from 436,824 UK […]