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      • Anita Kozyrskyj
      • Marie-Claire Arrieta
      • Tahsin Ferdous
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      • Shirin Afroj
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      • Dominique Bihan
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      • Sydney Morgan
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      • Jayne Danska
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      • Diego Silva
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      • Nicola Pett
  • Platforms
    • Platform 1: Gnotobiotic Animal Models & Intravital Microscopy
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      • Mouse Models Available
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Day: May 13, 2020

The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Fig 1. The perinatal period represents a time in development when exogenous factors that affect the microbiome such as antibiotics, diet, hygiene, pathogens, mode of birth, and pollutants can alter immune and physiological programming. The effects of early-life programming may lead to increased disease susceptibility later in life. Created with BioRender.com from The impact of maternal and early life malnutrition on health: a diet-microbe perspective.

Provide an overview of factors implicated in the progression of malnutrition during early life, discuss the microbiota that may contribute to health risk.

New Paper: Role of IRF8 in immune cells functions, protection against infections, and susceptibility to inflammatory diseases.

Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.

New Paper: Consumption of Artificially Sweetened Beverages During Pregnancy Impacts Infant Gut Microbiota and Body Mass Index

Fig 3. Drivers of gut bacterial beta-diversity and indicator taxa associated with maternal consumption of ASB differ between clusters. (A) Univariate models showing significance and explained variance of 10 variables on bacterial community structure across all data and each cluster subset. Horizontal bars show the amount of variance (R2) explained by each covariate in the model as determined by envfit. Asterisk denotes the significant covariates in each data subset (P

Study finds that artificially sweetened beverages consumption during pregnancy impacts mother’s microbiota and might lead to higher infant BMI.

New Paper: Maternal Distress During Pregnancy and Recurrence in Early Childhood Predicts Atopic Dermatitis and Asthma in Childhood

This population-based study shows sex-specific associations between maternal prenatal and postnatal distress, as well as the development of AD and asthma.

New Paper: Perivascular Localization of Macrophages in the Intestinal Mucosa is Regulated by Nr4a1 and the Microbiome

Fig 3. Gut microbiota affects the distribution and morphology of intestinal CX3CR1+ macrophages from the article Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome

A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.

The emerging roles of eosinophils in mucosal homeostasis.

Fig 1 - The emerging roles of eosinophils in mucosal homeostasis

A review of the critical role of eosinophils as regulators of mucosal homeostatic processes including immune maintenance, organ development and more.

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IMPACTT is funded by the Canadian Institutes of Health Research (CIHR) as part of the Canadian Microbiome Initiative 2 (CMI2)

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